Lexus
RX 350 4WD
U.S. fuel economy and specifications from the EPA.

19Best combined MPG2007 model year
2007–2009Model years3 with EPA ratings
6Rated configurationsDrive, transmission and engine
3.5 LEngine sizeDisplacement
Best combined MPG by model year
The highest EPA rating among each year's configurations.
2007 19 MPG
2008 19 MPG
2009 19 MPG
2 configurations.
4-Wheel or All-Wheel Drive · Automatic 5-spd
Premium gasoline · Sport Utility Vehicle - 4WD
- Combined MPG
- 19
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel or All-Wheel Drive · Automatic (S5)
Premium gasoline · Sport Utility Vehicle - 4WD
- Combined MPG
- 19
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel or All-Wheel Drive · Automatic 5-spd
Premium gasoline · Sport Utility Vehicle - 4WD
- Combined MPG
- 19
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel or All-Wheel Drive · Automatic (S5)
Premium gasoline · Sport Utility Vehicle - 4WD
- Combined MPG
- 19
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel or All-Wheel Drive · Automatic 5-spd
Premium gasoline · Sport Utility Vehicle - 4WD
- Combined MPG
- 19
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel or All-Wheel Drive · Automatic (S5)
Premium gasoline · Sport Utility Vehicle - 4WD
- Combined MPG
- 19
- Engine displacement
- 3.5 L
- Cylinders
- 6