Mercedes-Benz
CLS400 4matic
U.S. fuel economy and specifications from the EPA.

22Best combined MPG2015 model year
2015–2016Model years2 with EPA ratings
2Rated configurationsDrive, transmission and engine
3 LEngine sizeDisplacement
Best combined MPG by model year
The highest EPA rating among each year's configurations.
2015 22 MPG
2016 22 MPG
1 configuration.
4-Wheel Drive · Automatic 7-spd
Premium gasoline · Compact Cars
- Combined MPG
- 22
- Engine displacement
- 3.0 L
- Cylinders
- 6
4-Wheel Drive · Automatic 7-spd
Premium gasoline · Compact Cars
- Combined MPG
- 22
- Engine displacement
- 3.0 L
- Cylinders
- 6