Mercedes-Benz
E350 4matic (wagon)
U.S. fuel economy and specifications from the EPA.
22Best combined MPG2012 model year
2006–2016Model years10 with EPA ratings
10Rated configurationsDrive, transmission and engine
3.5 LEngine sizeDisplacement
Best combined MPG by model year
The highest EPA rating among each year's configurations.
2006 18 MPG
2007 18 MPG
2008 18 MPG
2009 18 MPG
2010 No rating
2011 19 MPG
2012 22 MPG
2013 22 MPG
2014 22 MPG
2015 22 MPG
2016 22 MPG
1 configuration.
4-Wheel Drive · Automatic 7-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 22
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel Drive · Automatic 7-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 22
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel Drive · Automatic 7-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 22
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel Drive · Automatic 7-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 22
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel Drive · Automatic 7-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 22
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel Drive · Automatic 7-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 19
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel or All-Wheel Drive · Automatic 5-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 18
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel or All-Wheel Drive · Automatic 5-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 18
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel or All-Wheel Drive · Automatic 5-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 18
- Engine displacement
- 3.5 L
- Cylinders
- 6
4-Wheel or All-Wheel Drive · Automatic 5-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 18
- Engine displacement
- 3.5 L
- Cylinders
- 6