Mercedes-Benz
E400 4matic (station wagon)
U.S. fuel economy and specifications from the EPA.

22Best combined MPG2015 model year
2015–2018Model years3 with EPA ratings
3Rated configurationsDrive, transmission and engine
3 LEngine sizeDisplacement
Best combined MPG by model year
The highest EPA rating among each year's configurations.
2015 22 MPG
2016 No rating
2017 21 MPG
2018 21 MPG
1 configuration.
4-Wheel Drive · Automatic 9-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 21
- Engine displacement
- 3.0 L
- Cylinders
- 6
4-Wheel Drive · Automatic 9-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 21
- Engine displacement
- 3.0 L
- Cylinders
- 6
4-Wheel Drive · Automatic 7-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 22
- Engine displacement
- 3.0 L
- Cylinders
- 6