Mercedes-Benz
E450 4matic All-Terrain (wagon)
U.S. fuel economy and specifications from the EPA.
25Best combined MPG2024 model year
2021–2027Model years7 with EPA ratings
7Rated configurationsDrive, transmission and engine
3 LEngine sizeDisplacement
Best combined MPG by model year
The highest EPA rating among each year's configurations.
2021 24 MPG
2022 24 MPG
2023 24 MPG
2024 25 MPG
2025 25 MPG
2026 25 MPG
2027 25 MPG
1 configuration.
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 25
- Engine displacement
- 3.0 L
- Cylinders
- 6
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 25
- Engine displacement
- 3.0 L
- Cylinders
- 6
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 25
- Engine displacement
- 3.0 L
- Cylinders
- 6
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 25
- Engine displacement
- 3.0 L
- Cylinders
- 6
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 24
- Engine displacement
- 3.0 L
- Cylinders
- 6
4-Wheel Drive · Automatic 9-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 24
- Engine displacement
- 3.0 L
- Cylinders
- 6
4-Wheel Drive · Automatic 9-spd
Premium gasoline · Midsize Station Wagons
- Combined MPG
- 24
- Engine displacement
- 3.0 L
- Cylinders
- 6