Mercedes-Benz
S450
U.S. fuel economy and specifications from the EPA.
22Best combined MPG2018 model year
2018–2020Model years3 with EPA ratings
3Rated configurationsDrive, transmission and engine
3 LEngine sizeDisplacement
Best combined MPG by model year
The highest EPA rating among each year's configurations.
2018 22 MPG
2019 22 MPG
2020 22 MPG
1 configuration.
Rear-Wheel Drive · Automatic 9-spd
Premium gasoline · Large Cars
- Combined MPG
- 22
- Engine displacement
- 3.0 L
- Cylinders
- 6
Rear-Wheel Drive · Automatic 9-spd
Premium gasoline · Large Cars
- Combined MPG
- 22
- Engine displacement
- 3.0 L
- Cylinders
- 6
Rear-Wheel Drive · Automatic 9-spd
Premium gasoline · Large Cars
- Combined MPG
- 22
- Engine displacement
- 3.0 L
- Cylinders
- 6