Mercedes-Benz
S580 4matic
U.S. fuel economy and specifications from the EPA.
21Best combined MPG2024 model year
2021–2027Model years7 with EPA ratings
7Rated configurationsDrive, transmission and engine
4 LEngine sizeDisplacement
Best combined MPG by model year
The highest EPA rating among each year's configurations.
2021 20 MPG
2022 19 MPG
2023 19 MPG
2024 21 MPG
2025 20 MPG
2026 20 MPG
2027 19 MPG
1 configuration.
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Large Cars
- Combined MPG
- 19
- Engine displacement
- 4.0 L
- Cylinders
- 8
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Large Cars
- Combined MPG
- 20
- Engine displacement
- 4.0 L
- Cylinders
- 8
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Large Cars
- Combined MPG
- 20
- Engine displacement
- 4.0 L
- Cylinders
- 8
2025 EPA test-car reference
Engine ratings from the EPA test-car reference.
| Engine rated hp | Displacement | Transmission | Drive |
|---|---|---|---|
| 496 | 4.0 L | Automatic · 9 gears | All Wheel Drive |
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Large Cars
- Combined MPG
- 21
- Engine displacement
- 4.0 L
- Cylinders
- 8
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Large Cars
- Combined MPG
- 19
- Engine displacement
- 4.0 L
- Cylinders
- 8
All-Wheel Drive · Automatic 9-spd
Premium gasoline · Large Cars
- Combined MPG
- 19
- Engine displacement
- 4.0 L
- Cylinders
- 8
4-Wheel Drive · Automatic 9-spd
Premium gasoline · Large Cars
- Combined MPG
- 20
- Engine displacement
- 4.0 L
- Cylinders
- 8